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Here, we propose a model for the mechanisms that underlie neuron responses in the auditory cortex. This study focuses on a cortical circuit involving excitatory and inhibitory (parvalbumin) neurons. Using physiologically relevant parameters in the proposed model network, we show that we can recreate observed results in live studies.more » « lessFree, publicly-accessible full text available July 1, 2026
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Fournier, Luke A; Phadke, Rhushikesh A; Salgado, Maria; Brack, Alison; Nocon, Jian Carlo; Bolshakova, Sonia; Grant, Jaylyn R; Padró_Luna, Nicole M; Sen, Kamal; Cruz-Martín, Alberto (, iScience)
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Nocon, Jian Carlo; Witter, Jake; Gritton, Howard; Han, Xue; Houghton, Conor; Sen, Kamal (, Journal of Neurophysiology)Little is known about how populations of neurons within cortical circuits encode sensory stimuli in the presence of competing stimuli at other spatial locations. Here, we investigate this problem in auditory cortex using a recently proposed information-theoretic approach. We find a small subset of neurons nearly maximizes information about target sounds in the presence of competing maskers, approaching information levels for isolated stimuli, and provides a noise-robust code for sounds in a complex auditory scene.more » « less